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Cytoplasmic linker proteins promote microtubule rescue in vivo

The role of plus end–tracking proteins in regulating microtubule (MT) dynamics was investigated by expressing a dominant negative mutant that removed endogenous cytoplasmic linker proteins (CLIPs) from MT plus ends. In control CHO cells, MTs exhibited asymmetric behavior: MTs persistently grew towar...

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Auteurs principaux: Komarova, Yulia A., Akhmanova, Anna S., Kojima, Shin-ichiro, Galjart, Niels, Borisy, Gary G.
Format: Artigo
Langue:Inglês
Publié: The Rockefeller University Press 2002
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2173097/
https://ncbi.nlm.nih.gov/pubmed/12446741
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200208058
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