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REF1/Aly and the additional exon junction complex proteins are dispensable for nuclear mRNA export

The metazoan proteins UAP56, REF1, and NXF1 are thought to bind sequentially to mRNA to promote its export to the cytoplasm: UAP56 is thought to recruit REF1 to nascent mRNA; REF1 acts as an adaptor protein mediating the association of NXF1 with mRNA, whereas NXF1 translocates the mRNA across the nu...

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Detalles Bibliográficos
Main Authors: Gatfield, David, Izaurralde, Elisa
Formato: Artigo
Idioma:Inglês
Publicado: The Rockefeller University Press 2002
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2173090/
https://ncbi.nlm.nih.gov/pubmed/12438415
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200207128
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