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Interference with the cytoplasmic tail of gp210 disrupts “close apposition” of nuclear membranes and blocks nuclear pore dilation

We tested the hypothesis that gp210, an integral membrane protein of nuclear pore complexes (NPCs), mediates nuclear pore formation. Gp210 has a large lumenal domain and small COOH-terminal tail exposed to the cytoplasm. We studied the exposed tail. We added recombinant tail polypeptides to Xenopus...

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Bibliografische gegevens
Hoofdauteurs: Drummond, Sheona P., Wilson, Katherine L.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: The Rockefeller University Press 2002
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2173024/
https://ncbi.nlm.nih.gov/pubmed/12093788
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200108145
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