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Ergosterol is required for targeting of tryptophan permease to the yeast plasma membrane
It was known that the uptake of tryptophan is reduced in the yeast erg6 mutant, which is defective in a late step of ergosterol biosynthesis. Here, we show that this is because the high affinity tryptophan permease Tat2p is not targeted to the plasma membrane. In wild-type cells, the plasma membrane...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Rockefeller University Press
2003
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2172991/ https://ncbi.nlm.nih.gov/pubmed/12810702 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200303088 |
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