Neurofilament heavy chain side arm phosphorylation regulates axonal transport of neurofilaments

Neurofilaments possess side arms that comprise the carboxy-terminal domains of neurofilament middle and heavy chains (NFM and NFH); that of NFH is heavily phosphorylated in axons. Here, we demonstrate that phosphorylation of NFH side arms is a mechanism for regulating transport of neurofilaments thr...

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Detalhes bibliográficos
Main Authors: Ackerley, Steven, Thornhill, Paul, Grierson, Andrew J., Brownlees, Janet, Anderton, Brian H., Leigh, P. Nigel, Shaw, Christopher E., Miller, Christopher C.J.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2003
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2172950/
https://ncbi.nlm.nih.gov/pubmed/12743103
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200303138
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