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Holey barrier: claudins and the regulation of brain endothelial permeability
Endothelial tight junctions (TJs) are an important functional part of the blood-brain barrier (BBB). In this issue, Nitta et al. (2003) demonstrate that claudin-5, a transmembrane protein of TJs, is a critical determinant of BBB permeability in mice. Unexpectedly, knockout of claudin-5 did not resul...
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| Auteurs principaux: | , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
The Rockefeller University Press
2003
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2172932/ https://ncbi.nlm.nih.gov/pubmed/12743096 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200304039 |
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