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Distinct in vivo roles for double-stranded RNA-binding domains of the Xenopus RNA-editing enzyme ADAR1 in chromosomal targeting

The RNA-editing enzyme adenosine deaminase that acts on RNA (ADAR1) deaminates adenosines to inosines in double-stranded RNA substrates. Currently, it is not clear how the enzyme targets and discriminates different substrates in vivo. However, it has been shown that the deaminase domain plays an imp...

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Enregistré dans:
Détails bibliographiques
Auteurs principaux: Doyle, Michael, Jantsch, Michael F.
Format: Artigo
Langue:Inglês
Publié: The Rockefeller University Press 2003
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2172894/
https://ncbi.nlm.nih.gov/pubmed/12719472
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200301034
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