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The roles of microtubule-based motor proteins in mitosis: comprehensive RNAi analysis in the Drosophila S2 cell line

Kinesins and dyneins play important roles during cell division. Using RNA interference (RNAi) to deplete individual (or combinations of) motors followed by immunofluorescence and time-lapse microscopy, we have examined the mitotic functions of cytoplasmic dynein and all 25 kinesins in Drosophila S2...

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Bibliographic Details
Main Authors: Goshima, Gohta, Vale, Ronald D.
Format: Artigo
Language:Inglês
Published: The Rockefeller University Press 2003
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2172859/
https://ncbi.nlm.nih.gov/pubmed/12975346
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200303022
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