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Interaction of Aurora-A and centrosomin at the microtubule-nucleating site in Drosophila and mammalian cells

A mitosis-specific Aurora-A kinase has been implicated in microtubule organization and spindle assembly in diverse organisms. However, exactly how Aurora-A controls the microtubule nucleation onto centrosomes is unknown. Here, we show that Aurora-A specifically binds to the COOH-terminal domain of a...

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Detalhes bibliográficos
Main Authors: Terada, Yasuhiko, Uetake, Yumi, Kuriyama, Ryoko
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2172831/
https://ncbi.nlm.nih.gov/pubmed/12939255
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200305048
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