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Differential αv integrin–mediated Ras-ERK signaling during two pathways of angiogenesis
Antagonists of αvβ3 and αvβ5 disrupt angiogenesis in response to bFGF and VEGF, respectively. Here, we show that these αv integrins differentially contribute to sustained Ras-extracellular signal–related kinase (Ras-ERK) signaling in blood vessels, a requirement for endothelial cell survival and ang...
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| Hauptverfasser: | , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
The Rockefeller University Press
2003
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2172815/ https://ncbi.nlm.nih.gov/pubmed/12952943 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200304105 |
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