Dynamic phosphoregulation of the cortical actin cytoskeleton and endocytic machinery revealed by real-time chemical genetic analysis

We used chemical genetics to control the activity of budding yeast Prk1p, which is a protein kinase that is related to mammalian GAK and AAK1, and which targets several actin regulatory proteins implicated in endocytosis. In vivo Prk1p inhibition blocked pheromone receptor endocytosis, and caused co...

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Главные авторы: Sekiya-Kawasaki, Mariko, Groen, Aaron Chris, Cope, M. Jamie T.V., Kaksonen, Marko, Watson, Hadiya A., Zhang, Chao, Shokat, Kevan M., Wendland, Beverly, McDonald, Kent L., McCaffery, J. Michael, Drubin, David G.
Формат: Artigo
Язык:Inglês
Опубликовано: The Rockefeller University Press 2003
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Report
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2172809/
https://ncbi.nlm.nih.gov/pubmed/12952930
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200305077
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