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The role of the lissencephaly protein Pac1 during nuclear migration in budding yeast

During mitosis in Saccharomyces cerevisiae, the mitotic spindle moves into the mother–bud neck via dynein-dependent sliding of cytoplasmic microtubules along the cortex of the bud. Here we show that Pac1, the yeast homologue of the human lissencephaly protein LIS1, plays a key role in this process....

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Autors principals: Lee, Wei-Lih, Oberle, Jessica R., Cooper, John A.
Format: Artigo
Idioma:Inglês
Publicat: The Rockefeller University Press 2003
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2172672/
https://ncbi.nlm.nih.gov/pubmed/12566428
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200209022
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