EPLIN regulates actin dynamics by cross-linking and stabilizing filaments

Epithelial protein lost in neoplasm (EPLIN) is a cytoskeleton-associated protein encoded by a gene that is down-regulated in transformed cells. EPLIN increases the number and size of actin stress fibers and inhibits membrane ruffling induced by Rac. EPLIN has at least two actin binding sites. Purifi...

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Bibliographic Details
Main Authors: Maul, Raymond S., Song, Yuhong, Amann, Kurt J., Gerbin, Sachi C., Pollard, Thomas D., Chang, David D.
Format: Artigo
Language:Inglês
Published: The Rockefeller University Press 2003
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2172667/
https://ncbi.nlm.nih.gov/pubmed/12566430
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200212057
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