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Roles of uroplakins in plaque formation, umbrella cell enlargement, and urinary tract diseases

The apical surface of mouse urothelium is covered by two-dimensional crystals (plaques) of uroplakin (UP) particles. To study uroplakin function, we ablated the mouse UPII gene. A comparison of the phenotypes of UPII- and UPIII-deficient mice yielded new insights into the mechanism of plaque formati...

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Detalhes bibliográficos
Main Authors: Kong, Xiang-Tian, Deng, Fang-Ming, Hu, Ping, Liang, Feng-Xia, Zhou, Ge, Auerbach, Anna B., Genieser, Nancy, Nelson, Peter K., Robbins, Edith S., Shapiro, Ellen, Kachar, Bechara, Sun, Tung-Tien
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2004
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2172608/
https://ncbi.nlm.nih.gov/pubmed/15611339
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200406025
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