Impact of telomerase ablation on organismal viability, aging, and tumorigenesis in mice lacking the DNA repair proteins PARP-1, Ku86, or DNA-PKcs

The DNA repair proteins poly(ADP-ribose) polymerase-1 (PARP-1), Ku86, and catalytic subunit of DNA-PK (DNA-PKcs) have been involved in telomere metabolism. To genetically dissect the impact of these activities on telomere function, as well as organismal cancer and aging, we have generated mice doubl...

Descripció completa

Guardat en:
Dades bibliogràfiques
Autors principals: Espejel, Silvia, Klatt, Peter, Murcia, Josiane Ménissier-de, Martín-Caballero, Juan, Flores, Juana M., Taccioli, Guillermo, de Murcia, Gilbert, Blasco, María A.
Format: Artigo
Idioma:Inglês
Publicat: The Rockefeller University Press 2004
Matèries:
Research Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2172587/
https://ncbi.nlm.nih.gov/pubmed/15545322
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200407178
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars