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Invadolysin: a novel, conserved metalloprotease links mitotic structural rearrangements with cell migration

The cell cycle is widely known to be regulated by networks of phosphorylation and ubiquitin-directed proteolysis. Here, we describe IX-14/invadolysin, a novel metalloprotease present only in metazoa, whose activity appears to be essential for mitotic progression. Mitotic neuroblasts of Drosophila me...

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Detalhes bibliográficos
Main Authors: McHugh, Brian, Krause, Sue A., Yu, Bin, Deans, Anne-Marie, Heasman, Sarah, McLaughlin, Paul, Heck, Margarete M.S.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2004
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2172566/
https://ncbi.nlm.nih.gov/pubmed/15557119
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200405155
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