Requirement of plakophilin 2 for heart morphogenesis and cardiac junction formation

Plakophilins are proteins of the armadillo family that function in embryonic development and in the adult, and when mutated can cause disease. We have ablated the plakophilin 2 gene in mice. The resulting mutant mice exhibit lethal alterations in heart morphogenesis and stability at mid-gestation (E...

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Bibliografiska uppgifter
Huvudupphovsmän: Grossmann, Katja S., Grund, Christine, Huelsken, Joerg, Behrend, Martin, Erdmann, Bettina, Franke, Werner W., Birchmeier, Walter
Materialtyp: Artigo
Språk:Inglês
Publicerad: The Rockefeller University Press 2004
Ämnen:
Research Articles
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2172504/
https://ncbi.nlm.nih.gov/pubmed/15479741
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200402096
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