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Requirement of plakophilin 2 for heart morphogenesis and cardiac junction formation

Plakophilins are proteins of the armadillo family that function in embryonic development and in the adult, and when mutated can cause disease. We have ablated the plakophilin 2 gene in mice. The resulting mutant mice exhibit lethal alterations in heart morphogenesis and stability at mid-gestation (E...

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Detalhes bibliográficos
Main Authors: Grossmann, Katja S., Grund, Christine, Huelsken, Joerg, Behrend, Martin, Erdmann, Bettina, Franke, Werner W., Birchmeier, Walter
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2004
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2172504/
https://ncbi.nlm.nih.gov/pubmed/15479741
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200402096
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