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Human Rif1 protein binds aberrant telomeres and aligns along anaphase midzone microtubules
We identified and characterized a human orthologue of Rif1 protein, which in budding yeast interacts in vivo with the major duplex telomeric DNA binding protein Rap1p and negatively regulates telomere length. Depletion of hRif1 by RNA interference in human cancer cells impaired cell growth but had n...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
The Rockefeller University Press
2004
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2172464/ https://ncbi.nlm.nih.gov/pubmed/15583028 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200408181 |
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