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Novel regulation of mitotic exit by the Cdc42 effectors Gic1 and Gic2

The guanine nucleotide exchange factor Cdc24, the GTPase Cdc42, and the Cdc42 effectors Cla4 and Ste20, two p21-activated kinases, form a signal transduction cascade that promotes mitotic exit in yeast. We performed a genetic screen to identify components of this pathway. Two related bud cortex–asso...

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Autori principali: Höfken, Thomas, Schiebel, Elmar
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Rockefeller University Press 2004
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2172333/
https://ncbi.nlm.nih.gov/pubmed/14734533
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200309080
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