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A divergent canonical WNT-signaling pathway regulates microtubule dynamics: Dishevelled signals locally to stabilize microtubules

Dishevelled (DVL) is associated with axonal microtubules and regulates microtubule stability through the inhibition of the serine/threonine kinase, glycogen synthase kinase 3β (GSK-3β). In the canonical WNT pathway, the negative regulator Axin forms a complex with β-catenin and GSK-3β, resulting in...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Ciani, Lorenza, Krylova, Olga, Smalley, Matthew J., Dale, Trevor C., Salinas, Patricia C.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: The Rockefeller University Press 2004
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2172322/
https://ncbi.nlm.nih.gov/pubmed/14734535
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200309096
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