LCK-phosphorylated human killer cell-inhibitory receptors recruit and activate phosphatidylinositol 3-kinase

HLA-specific killer cell inhibitory receptors (KIR) are thought to impede natural killer (NK) and T cell activation programs through recruitment of the SH2 domain-containing tyrosine phosphatases, SHP-1 and SHP-2, to their cytoplasmic tails (CYT). To identify other SH2 domain-containing proteins tha...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Marti, Francesc, Xu, C. Wilson, Selvakumar, Annamalai, Brent, Roger, Dupont, Bo, King, Philip D.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1998
Assuntos:	Biological Sciences
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC21722/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9751747/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.95.20.11810
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