ERK activation promotes neuronal degeneration predominantly through plasma membrane damage and independently of caspase-3

Our recent studies have shown that extracellular-regulated protein kinase (ERK) promotes cell death in cerebellar granule neurons (CGN) cultured in low potassium. Here we report that the “death” phenotypes of CGN after potassium withdrawal are heterogeneous, allowing the distinction between plasma m...

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Detalhes bibliográficos
Main Authors: Subramaniam, Srinivasa, Zirrgiebel, Ute, von Bohlen und Halbach, Oliver, Strelau, Jens, Laliberté, Christine, Kaplan, David R., Unsicker, Klaus
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2004
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2172179/
https://ncbi.nlm.nih.gov/pubmed/15123736
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200403028
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