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Localization of the AP-3 adaptor complex defines a novel endosomal exit site for lysosomal membrane proteins

The adaptor protein (AP) 3 adaptor complex has been implicated in the transport of lysosomal membrane proteins, but its precise site of action has remained controversial. Here, we show by immuno-electron microscopy that AP-3 is associated with budding profiles evolving from a tubular endosomal compa...

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Библиографические подробности
Главные авторы: Peden, Andrew A., Oorschot, Viola, Hesser, Boris A., Austin, Cary D., Scheller, Richard H., Klumperman, Judith
Формат: Artigo
Язык:Inglês
Опубликовано: The Rockefeller University Press 2004
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2172074/
https://ncbi.nlm.nih.gov/pubmed/15051738
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200311064
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