PKCα mediates TGFβ-induced growth inhibition of human keratinocytes via phosphorylation of S100C/A11

Growth regulation of epithelial cells is of major concern because most human cancers arise from them. We demonstrated previously a novel signal pathway involving S100C/A11 for high Ca(2+)-induced growth inhibition of normal human keratinocytes (Sakaguchi, M., M. Miyazaki, M. Takaishi, Y. Sakaguchi,...

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Main Authors: Sakaguchi, Masakiyo, Miyazaki, Masahiro, Sonegawa, Hiroyuki, Kashiwagi, Mariko, Ohba, Motoi, Kuroki, Toshio, Namba, Masayoshi, Huh, Nam-ho
Format: Artigo
Language:Inglês
Published: The Rockefeller University Press 2004
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2172059/
https://ncbi.nlm.nih.gov/pubmed/15051732
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200312041
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