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Superoxide is a mediator of an altruistic aging program in Saccharomyces cerevisiae

Aging is believed to be a nonadaptive process that escapes the force of natural selection. Here, we challenge this dogma by showing that yeast laboratory strains and strains isolated from grapes undergo an age- and pH-dependent death with features of mammalian programmed cell death (apoptosis). Afte...

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Autors principals: Fabrizio, Paola, Battistella, Luisa, Vardavas, Raffaello, Gattazzo, Cristina, Liou, Lee-Loung, Diaspro, Alberto, Dossen, Janis W., Gralla, Edith Butler, Longo, Valter D.
Format: Artigo
Idioma:Inglês
Publicat: The Rockefeller University Press 2004
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2172019/
https://ncbi.nlm.nih.gov/pubmed/15452146
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200404002
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