β1 integrin and IL-3R coordinately regulate STAT5 activation and anchorage-dependent proliferation

We previously demonstrated that integrin-dependent adhesion activates STAT5A, a well known target of IL-3–mediated signaling. Here, we show that in endothelial cells the active β1 integrin constitutively associates with the unphosphorylated IL-3 receptor (IL-3R) β common subunit. This association is...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Defilippi, Paola, Rosso, Arturo, Dentelli, Patrizia, Calvi, Cristina, Garbarino, Giovanni, Tarone, Guido, Pegoraro, Luigi, Brizzi, Maria Felice
Médium: Artigo
Jazyk:Inglês
Vydáno: The Rockefeller University Press 2005
Témata:
Research Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2171831/
https://ncbi.nlm.nih.gov/pubmed/15795318
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200405116
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky