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The LIM protein Ajuba influences p130Cas localization and Rac1 activity during cell migration

Cell migration requires extension of lamellipodia that are stabilized by formation of adhesive complexes at the leading edge. Both processes are regulated by signaling proteins recruited to nascent adhesive sites that lead to activation of Rho GTPases. The Ajuba/Zyxin family of LIM proteins are comp...

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Autori principali: Pratt, Stephen J., Epple, Holly, Ward, Michael, Feng, Yunfeng, Braga, Vania M., Longmore, Gregory D.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Rockefeller University Press 2005
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2171823/
https://ncbi.nlm.nih.gov/pubmed/15728191
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200406083
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