Regulation of the interaction between PIPKIγ and talin by proline-directed protein kinases

The interaction of talin with phosphatidylinositol(4) phosphate 5 kinase type Iγ (PIPKIγ) regulates PI(4,5)P(2) synthesis at synapses and at focal adhesions. Here, we show that phosphorylation of serine 650 (S650) within the talin-binding sequence of human PIPKIγ blocks this interaction. At synapses...

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Main Authors: Lee, Sang Yoon, Voronov, Sergey, Letinic, Kresimir, Nairn, Angus C., Di Paolo, Gilbert, De Camilli, Pietro
Formáid: Artigo
Teanga:Inglês
Foilsithe: The Rockefeller University Press 2005
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Research Articles
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2171813/
https://ncbi.nlm.nih.gov/pubmed/15738269
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200409028
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