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Regulation of α5β1 integrin conformation and function by urokinase receptor binding
Urokinase-type plasminogen activator receptors (uPARs), up-regulated during tumor progression, associate with β1 integrins, localizing urokinase to sites of cell attachment. Binding of uPAR to the β-propeller of α3β1 empowers vitronectin adhesion by this integrin. How uPAR modifies other β1 integrin...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Rockefeller University Press
2005
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2171741/ https://ncbi.nlm.nih.gov/pubmed/15684035 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200404112 |
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