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HECT ubiquitin ligases link viral and cellular PPXY motifs to the vacuolar protein-sorting pathway
Many enveloped viruses exploit the class E vacuolar protein-sorting (VPS) pathway to bud from cells, and use peptide motifs to recruit specific class E VPS factors. Homologous to E6AP COOH terminus (HECT) ubiquitin ligases have been implicated as cofactors for PPXY motif–dependent budding, but preci...
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Main Authors: | , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
The Rockefeller University Press
2005
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2171676/ https://ncbi.nlm.nih.gov/pubmed/15623582 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200408155 |
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