Methyl CpG–binding proteins induce large-scale chromatin reorganization during terminal differentiation

Pericentric heterochromatin plays an important role in epigenetic gene regulation. We show that pericentric heterochromatin aggregates during myogenic differentiation. This clustering leads to the formation of large chromocenters and correlates with increased levels of the methyl CpG–binding protein...

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Bibliografische gegevens
Hoofdauteurs: Brero, Alessandro, Easwaran, Hariharan P., Nowak, Danny, Grunewald, Ingrid, Cremer, Thomas, Leonhardt, Heinrich, Cardoso, M. Cristina
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: The Rockefeller University Press 2005
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Research Articles
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2171616/
https://ncbi.nlm.nih.gov/pubmed/15939760
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200502062
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