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Reaching out for signals: filopodia sense EGF and respond by directed retrograde transport of activated receptors
ErbB1 receptors situated on cellular filopodia undergo systematic retrograde transport after binding of the epidermal growth factor (EGF) and activation of the receptor tyrosine kinase. Specific inhibitors of the erbB1 receptor tyrosine kinase as well as cytochalasin D, a disruptor of the actin cyto...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Rockefeller University Press
2005
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2171515/ https://ncbi.nlm.nih.gov/pubmed/16103229 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200503140 |
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