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Reversible intracellular translocation of KRas but not HRas in hippocampal neurons regulated by Ca(2+)/calmodulin

The Ras/MAPK pathway regulates synaptic plasticity and cell survival in neurons of the central nervous system. Here, we show that KRas, but not HRas, acutely translocates from the plasma membrane (PM) to the Golgi complex and early/recycling endosomes in response to neuronal activity. Translocation...

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Detalhes bibliográficos
Main Authors: Fivaz, Marc, Meyer, Tobias
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2171478/
https://ncbi.nlm.nih.gov/pubmed/16043511
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200409157
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