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Essential role of CIB1 in regulating PAK1 activation and cell migration
p21-activated kinases (PAKs) regulate many cellular processes, including cytoskeletal rearrangement and cell migration. In this study, we report a direct and specific interaction of PAK1 with a 22-kD Ca(2+)-binding protein, CIB1, which results in PAK1 activation both in vitro and in vivo. CIB1 binds...
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| Autors principals: | , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
The Rockefeller University Press
2005
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2171473/ https://ncbi.nlm.nih.gov/pubmed/16061695 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200502090 |
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