The limited role of NH(2)-terminal c-Jun phosphorylation in neuronal apoptosis: Identification of the nuclear pore complex as a potential target of the JNK pathway

c-Jun is induced in many neuronal death paradigms. A critical step in c-Jun regulation involves phosphorylation of Ser63/Ser73 located in the NH(2)-terminal transactivation domain. To determine the importance of this phosphorylation for neuronal apoptosis, we analyzed the sympathetic neurons of mice...

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Bibliografiska uppgifter
Huvudupphovsmän: Besirli, Cagri G., Wagner, Erwin F., Johnson, Eugene M.
Materialtyp: Artigo
Språk:Inglês
Publicerad: The Rockefeller University Press 2005
Ämnen:
Research Articles
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2171472/
https://ncbi.nlm.nih.gov/pubmed/16061693
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200501138
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