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Ubiquitin/SUMO modification of PCNA promotes replication fork progression in Xenopus laevis egg extracts

The homotrimeric DNA replication protein proliferating cell nuclear antigen (PCNA) is regulated by both ubiquitylation and sumoylation. We study the appearance and the impact of these modifications on chromosomal replication in frog egg extracts. Xenopus laevis PCNA is modified on lysine 164 by sumo...

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Detalhes bibliográficos
Main Authors: Leach, Craig A., Michael, W. Matthew
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2171325/
https://ncbi.nlm.nih.gov/pubmed/16344309
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200508100
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