Desmoplakin assembly dynamics in four dimensions: multiple phases differentially regulated by intermediate filaments and actin

The intermediate filament (IF)–binding protein desmoplakin (DP) is essential for desmosome function and tissue integrity, but its role in junction assembly is poorly understood. Using time-lapse imaging, we show that cell–cell contact triggers three temporally overlapping phases of DP-GFP dynamics:...

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Detalhes bibliográficos
Main Authors: Godsel, Lisa M., Hsieh, Sherry N., Amargo, Evangeline V., Bass, Amanda E., Pascoe-McGillicuddy, Lauren T., Huen, Arthur C., Thorne, Meghan E., Gaudry, Claire A., Park, Jung K., Myung, Kyunghee, Goldman, Robert D., Chew, Teng-Leong, Green, Kathleen J.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2005
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Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2171300/
https://ncbi.nlm.nih.gov/pubmed/16365169
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200510038
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