Oxypurinol improves coronary and peripheral endothelial function in patients with coronary artery disease

Coronary endothelial dysfunction is a powerful prognostic marker in patients with coronary artery disease (CAD) that is centrally related to oxidative inhibition of nitric oxide (NO)-dependent vascular cell signaling. Xanthine oxidase (XO), which both binds to and is expressed by endothelial cells,...

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Bibliographische Detailangaben
Hauptverfasser: Baldus, Stephan, Köster, Ralf, Chumley, Phillip, Heitzer, Thomas, Rudolph, Volker, Ostad, Mir Abolfazl, Warnholtz, Ascan, Staude, Hans-Jürgen, Thuneke, Felix, Koss, Klaus, Berger, Jürgen, Meinertz, Thomas, Freeman, Bruce A., Münzel, Thomas
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2005
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2170895/
https://ncbi.nlm.nih.gov/pubmed/16214034
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2005.06.004
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