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Non-coding MicroRNAs hsa-let-7g and hsa-miR-181b are Associated with Chemoresponse to S-1 in Colon Cancer

BACKGROUND: MicroRNAs (miRNAs) are small non-coding RNAs (~22 nucleotides) that regulate gene expression at a post-transcriptional level via imperfect base pairing to the 3’-UTR of their target mRNAs. Previous studies from our group identified a number of deregulated miRNAs due to the loss of p53 tu...

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Bibliographic Details
Main Authors: Nakajima, Go, Hayashi, Kazuhiko, Xi, Yaguang, Kudo, Kenji, Uchida, Kazumi, Takasaki, Ken, Yamamoto, Masakazu, Ju, Jingfang
Format: Artigo
Language:Inglês
Published: 2006
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2170889/
https://ncbi.nlm.nih.gov/pubmed/18172508
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