Gene Expression Profile of Neuronal Progenitor Cells Derived from hESCs: Activation of Chromosome 11p15.5 and Comparison to Human Dopaminergic Neurons

BACKGROUND: We initiated differentiation of human embryonic stem cells (hESCs) into dopamine neurons, obtained a purified population of neuronal precursor cells by cell sorting, and determined patterns of gene transcription. METHODOLOGY: Dopaminergic differentiation of hESCs was initiated by culturi...

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Hauptverfasser: Freed, William J., Chen, Jia, Bäckman, Cristina M., Schwartz, Catherine M., Vazin, Tandis, Cai, Jingli, Spivak, Charles E., Lupica, Carl R., Rao, Mahendra S., Zeng, Xianmin
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2008
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2170519/
https://ncbi.nlm.nih.gov/pubmed/18183302
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0001422
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