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Surface polyethylene glycol enhances substrate-mediated gene delivery by nonspecifically immobilized complexes

Substrate-mediated gene delivery describes the immobilization of gene therapy vectors to a biomaterial, which enhances gene transfer by exposing adhered cells to elevated DNA concentrations within the local microenvironment. Surface chemistry has been shown to affect transfection by nonspecifically...

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Bibliographic Details
Main Authors: Pannier, Angela K., Wieland, Julie A., Shea, Lonnie D.
Format: Artigo
Language:Inglês
Published: 2007
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2170460/
https://ncbi.nlm.nih.gov/pubmed/17920004
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.actbio.2007.08.008
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