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Dominantly inherited proximal myotonic myopathy and leukoencephalopathy in a family with an incidental CLCN1 mutation

A two generation family of Greek origin with mild myotonia, predominantly proximal muscle weakness, and cataracts compatible with the syndrome of proximal myotonic myopathy, is reported. In addition, brain MRI showed a diffuse leukoencephalopathy in the propositus. Molecular genetic studies showed t...

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Autors principals: Mastaglia, F, Harker, N, Phillips, B, Day, T, Hankey, G, Laing, N, Fabian, V, Kakulas, B
Format: Artigo
Idioma:Inglês
Publicat: BMJ Group 1998
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2170056/
https://ncbi.nlm.nih.gov/pubmed/9576553
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