Alterations in local chromatin environment are involved in silencing and activation of subtelomeric var genes in Plasmodium falciparum

Plasmodium falciparum erythrocyte membrane protein 1 (PfEMP1), encoded by the var gene family, undergoes antigenic variation and plays an important role in chronic infection and severe malaria. Only a single var gene is transcribed per parasite, and epigenetic control mechanisms are fundamental in t...

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Detaylı Bibliyografya
Asıl Yazarlar: Voss, Till S, Tonkin, Christopher J, Marty, Allison J, Thompson, Jennifer K, Healer, Julie, Crabb, Brendan S, Cowman, Alan F
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Blackwell Publishing Ltd 2007
Konular:
Research Articles
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2169929/
https://ncbi.nlm.nih.gov/pubmed/17725559
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2958.2007.05899.x
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