Trypanosoma brucei Polo-like kinase is essential for basal body duplication, kDNA segregation and cytokinesis

Polo-like kinases (PLKs) are conserved eukaryotic cell cycle regulators, which play multiple roles, particularly during mitosis. The function of Trypanosoma brucei PLK was investigated in procyclic and bloodstream-form parasites. In procyclic trypanosomes, RNA interference (RNAi) of PLK, or overexpr...

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Autores principales: Hammarton, Tansy C, Kramer, Susanne, Tetley, Laurence, Boshart, Michael, Mottram, Jeremy C
Formato: Artigo
Lenguaje:Inglês
Publicado: Blackwell Publishing Ltd 2007
Materias:
Research Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2169650/
https://ncbi.nlm.nih.gov/pubmed/17662039
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2958.2007.05866.x
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