DNA vaccines encoding IL-2 linked to HPV-16 E7 antigen generate enhanced E7-specific CTL responses and antitumor activity

DNA vaccination has emerged as a promising strategy for cancer immunotherapy. However, since DNA vaccines have low immunogenicity, various strategies have been developed to enhance the potency of DNA vaccines. In the current study, we aim to determine whether the potency of the DNA vaccine encoding...

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Bibliographische Detailangaben
Hauptverfasser: Lin, Cheng-Tao, Tsai, Ya-Chea, He, Liangmei, Yeh, Chun-Nan, Chang, Ting-Chang, Soong, Yung-Kuei, Monie, Archana, Hung, Chien-Fu, Lai, Chyong-Huey
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2007
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2169502/
https://ncbi.nlm.nih.gov/pubmed/17976741
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.imlet.2007.09.008
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