Afadin: A Key Molecule Essential for Structural Organization of Cell–Cell Junctions of Polarized Epithelia during Embryogenesis

Afadin is an actin filament–binding protein that binds to nectin, an immunoglobulin-like cell adhesion molecule, and is colocalized with nectin at cadherin-based cell–cell adherens junctions (AJs). To explore the function of afadin in cell–cell adhesion during embryogenesis, we generated afadin(−/−)...

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Hauptverfasser: Ikeda, Wataru, Nakanishi, Hiroyuki, Miyoshi, Jun, Mandai, Kenji, Ishizaki, Hiroyoshi, Tanaka, Miki, Togawa, Atushi, Takahashi, Kenichi, Nishioka, Hideo, Yoshida, Hisahiro, Mizoguchi, Akira, Nishikawa, Shin-ichi, Takai, Yoshimi
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Rockefeller University Press 1999
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Original Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2169488/
https://ncbi.nlm.nih.gov/pubmed/10477764
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