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Mammalian ASH1L Is a Histone Methyltransferase That Occupies the Transcribed Region of Active Genes

Histone lysine methylation regulates genomic functions, including gene transcription. Previous reports found various degrees of methylation at H3K4, H3K9, and H4K20 within the transcribed region of active mammalian genes. To identify the enzymes responsible for placing these modifications, we examin...

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Detalhes bibliográficos
Main Authors: Gregory, Gregory D., Vakoc, Christopher R., Rozovskaia, Tanya, Zheng, Xingwu, Patel, Shetal, Nakamura, Tatsuya, Canaani, Eli, Blobel, Gerd A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2169421/
https://ncbi.nlm.nih.gov/pubmed/17923682
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00993-07
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