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Histone Deacetylase 6 Regulates Growth Factor-Induced Actin Remodeling and Endocytosis

Histone deacetylase 6 (HDAC6) is a cytoplasmic deacetylase that uniquely catalyzes α-tubulin deacetylation and promotes cell motility. However, the mechanism underlying HDAC6-dependent cell migration and the role for microtubule acetylation in motility are not known. Here we show that HDAC6-induced...

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Detalhes bibliográficos
Main Authors: Gao, Ya-sheng, Hubbert, Charlotte C., Lu, Jianrong, Lee, Yi-Shan, Lee, Joo-Yong, Yao, Tso-Pang
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2007
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2169396/
https://ncbi.nlm.nih.gov/pubmed/17938201
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00393-07
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