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Isolated HIV-1 core is active for reverse transcription

Whether purified HIV-1 virion cores are capable of reverse transcription or require uncoating to be activated is currently controversial. To address this question we purified cores from a virus culture and tested for the ability to generate authentic reverse transcription products. A dense fraction...

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Detalhes bibliográficos
Main Authors: Warrilow, David, Stenzel, Deborah, Harrich, David
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2169257/
https://ncbi.nlm.nih.gov/pubmed/17956635
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-4690-4-77
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