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Crimean-Congo Hemorrhagic Fever Virus Glycoprotein Processing by the Endoprotease SKI-1/S1P Is Critical for Virus Infectivity

Crimean-Congo hemorrhagic fever virus (CCHFV) causes severe human disease. The CCHFV medium RNA encodes a polyprotein which is proteolytically processed to yield the glycoprotein precursors PreGn and PreGc, followed by structural glycoproteins Gn and Gc. Subtilisin kexin isozyme-1/site-1 protease (S...

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Bibliografske podrobnosti
Main Authors: Bergeron, Éric, Vincent, Martin J., Nichol, Stuart T.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology (ASM) 2007
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2169102/
https://ncbi.nlm.nih.gov/pubmed/17898072
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01647-07
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